The microbiome

The tiny things that make our lives unique

Each person’s health requires unique care.

Have you ever wondered...
Weight
Easy to get fat VS difficult to get fat. What causes the difference?
Diarrhea
Why you frequently have diarrhea despite eating like your friends?
Constipation
Why you’re often constipating despite eating lots of vegetables?
Tooth Decay
Why your tooth still decays despite seldom eating sweet and frequently brushing?
Allergies
When your recurring allergies will ever end?
Flu
Why you easily contract cold from others who have it?
Microbiomes
Tiny lives that have always been misunderstood

Do microbiomes depend on us, or vice versa?

Did you know that there are between 30-400 trillion microbes, including bacteria, viruses and fungi, living in the human digestive system? That’s 1.1 times our total body cell count. Which is why we call this microbiome our 33rd organ, as it is necessary for proper function of many body systems.

Don’t get me wrong

When mentioning microbes or bacteria, most people view them as a health threat. But in fact, both beneficial and harmful bacteria exist, and our health will be negatively impacted when an imbalance occurs — such as having too few beneficial bacteria to control the harmful ones. Beneficial bacteria are necessary for our well-being because they stimulate our immune system, feed our cells, and protect us from other harmful bacteria as well as viruses.

When gut microbiome are in imbalance
Inflammation
Inflammation
Microbiome imbalances often lead to build-up of harmful bacteria which releases toxins that breakdown mucosal cells along gut linings, making it easy for these bacteria to enter your gut’s inner layers and trigger inflammation when your immune system responds.
Insomnia
Insomnia
When there’s an imbalance in gut microbiome, the beneficial bacteria will be replaced with harmful ones. This causes a decrease in production of vitamins and neurotransmitter chemicals (e.g., serotonin, dopamine, and GABA) due to lesser bacteria to produce them. As a result, your sleep can be affected.
Allergies
Immune Deficiency
Maintaining the balance of gut microbiome helps strengthen your resistance to diseases. When bacteria along the gut lining decreases, harmful bacteria can easily enter and cause mucosal cell damage as well as release inflammatory chemicals and prevent immune response by intestinal cells.
Indigestion
Indigestion
When digested food reaches the large intestines, the bacteria there will break down the remaining food fibers. But an imbalance in microbiome can slow down this process and affect bowel movement. Harmful bacteria in the small intestines will also increase, causing bloating and indigestion.
Constipation
Irregular Bowel Movement
When food is not properly broken down due to a lesser variety of food-digesting bacteria, the food will remain in the intestines longer than usual and cause irritable bowel syndrome.
Weight
Poor Metabolism
When overeating, the human digestive system can’t digest effectively. Any remaining food will then be broken down by various bacteria with different digestive enzymes. But when an imbalance occurs due to a lack of certain bacteria, there will be insufficient enzymes produced to properly digest the food, causing irregular metabolism and indigestion.
Causes of microbiome imbalance
Avatar Food
The food you eat
Frequent intake of food with flour and high fat content or instant food with preservatives and insecticide may reduce the beneficial bacteria in your gut.
Avatar Lifestyle
Lifestyle
Such as insomnia, stress, and insufficient exercise.
Avatar Antibiotics
Taking Antibiotics
Long-term continuous consumption of antibiotics can cause an imbalance in microbiome culture. Because our gut are full of different types of bacteria, both beneficial and harmful ones, frequently taking antibiotics can completely kill off both kinds making it easy to contract diseases.
Where do the microbiomes inside us come from?

A mother’s womb serves as a shield from bacteria and viruses. When we’re born, we pick up various microbiome instantly, depending on the method of birth and where it took place.

Bacteria starts entering a baby as soon as water breaks.
A baby that’s given a natural birth will pick up microbes and bacteria directly from the mother’s birth canal. But if given birth through operation, the baby will pick up microbes and bacteria from skin contact with the mother, doctor and nurses performing the operation.

Breastfed vs. Formula milk
A breastfed baby will receive antibodies from the mother, reducing risks of having allergies. But a baby fed with formula milk will not receive this immunity.

What are probiotics, prebiotics, and postbiotics?

Probiotics
Our body has microbiome or bacteria that are beneficial to our well-being called probiotics. They can be found in yoghurt, kimchi, natto, and miso.



Prebiotics
These are food for our probiotics, mostly found in food that’s high in fiber and can’t be digested such as garlic, onions, red beans and various fruits and vegetables.



Postbiotics
These are chemicals produced by probiotics that improves efficiency of our body’s various system functions such as the immune system, digestive system, and weight control.

How connected are your gut and brain?

Studies show that there’s a linkage between gut inflammation and emotional well-being. Patients with food-related illnesses can also suffer from depression and anxiety.

Microbiome and bacteria in our digestive system can affect our ability to sleep.
Communication of the Gut-Brain Axis, which transfers data between our guts and brain, is dependent on microbiome functions and controls our sleep genes including serotonin, a chemical necessary for brain and neural functions which affects our thinking, behaviors, mood and ability to sleep.

Personalized Care
Because our microbiomes are different Even if we’re in the same place eating the same menu, the microbiome in our bodies have different standards, which is why the health care plan needs to differ. Come get to know the microbiomes inside you so that we can develop the most suitable health care for you.
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Gut Microbiome TestTake-home test kits that help you get to know your gut, allowing you to have your own personalized healthcare solution.
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Probiotics++Probiotics++ supplements designed to help with specific symptoms, containing prebiotics, probiotics, and postbiotics.
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SubscriptionBundled packages that contain test kits, probiotics supplements, and tele-consultation with a doctor or human microbiome expert.
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Weight managementAnalyze your gut microbiome to determine factors related to weight management, such as food to avoid, and microbiomes related to hunger and metabolism.
Modgut Co., Ltd110/1 KX Knowledge Exchange Center, Floor 14, Room 1423, Krung Thon Buri Road, Bang Lamp Lang, Khlong San, Bangkok 10600
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